Minos Kritikos, Ph.D.

Dr. Kritikos is a neuroscientist in the Program in Public Health and the World Trade Center Health Program. His interests and expertise include neurobiological mechanisms of synaptic plasticity, learning and memory, cognitive aging, and dementia. His current research focuses on PET/MRI neuroimaging, central and peripheral biomarkers of dementia, and neurocognitive, neurobehavioral, and neuromotor performance as symptoms of neurodegenerative disease in late life. His studies are attempting to further our understanding of the underlying etiology for the observed mild cognitive impairment and dementia emerging in 9/11 responders.

Education:

Ph.D., Neuroscience, Bristol University, UK (2013)

MSc, Molecular Neuroscience, Bristol University (2009)

BSc, Neuroscience and Psychology, Keele University, UK (2005-2008)

Professional Experience:

• Senior Research Scientist, Program in Public Health, Stony Brook Medicine, 2023-present
• Research Scientist, Program in Public Health, Stony Brook Medicine,2019-2023
• Lecturer, University of Nicosia, Cyprus, 2015-2018
• Research Fellow, University of Cambridge, 2013-2015

Selected Publications:

Kritikos M, Clouston SAP, Huang C, Pellecchia AC, Meija-Santiago S, Carr AM, Kotov R, Lucchini RG, Gandy SE, Bromet EJ, Luft BJ. Cortical Complexity in World Trade Center Responders with Chronic Postraumatic Stress Disorder. Translation Psychiatry (In Press).

Kritikos M, Franceschi AM, Vaska P, Clouston SAP, Huang C, Salerno M, Deri Y, Tang C, Pellecchia A, Meija-Santiago S, Sano M, Bromet EJ, Lucchini RG, Gandy SE, Luft BJ. Assessment of Alzheimer’s Diseaser Imaging Biomarkers in World Trafe Center Responders with Cognitive Impairment at Midlife. World Journal of Nuclear Medicine (In Press).

Sean A. P. Clouston, Charles B. Hall, Minos Kritikos, David Bennett, et al., Cognitive impairment and World Trade Centre-related exposures. Nature Reviews Neurology (In Press).

Allen P F Chen, Sean A P Clouston, Minos Kritikos, Lauren Richmond, Jaymie Meliker, Frank Mann, Stephanie Santiago-Michels, Alison C Pellecchia, Melissa A Carr, Pei-Fen Kuan, Evelyn J Bromet, Benjamin J Luft. A deep learning approach for monitoring parietal-dominant Alzheimer’s disease in World Trade Center responders at midlife. Brain Communications, Volume 3, Issue 3, 2021.

Huang, Chuana, Kritikos, Minos, Clouston, Sean A.P., Deri, Yael, Serrano-Sosa, Mario, Bangiyev, Lev, Santiago-Michels, Stephanie, Gandy, Sam, Sano, Mary, Bromet, Evelyn J, Luft, Benjamin J. White Matter Connectivity in Incident Mild Cognitive Impairment: A Diffusion Spectrum Imaging Study of World Trade Center Responders at Midlife. Journal of Alzheimer's Disease, vol. 80, no. 3, pp. 1209-1219, 2021.

Diminich ED, Clouston SAP, Kranidis A, Kritikos M, Kotov R, Kuan P, Carr M, Bromet EJ, Luft BJ. Chronic Posttraumatic Stress Disorder and Comorbid Cognitive and Physical Impairments in World Trade Center Responders. J Trauma Stress. 2021 Jun;34(3):616-627. doi: 10.1002/jts.22631. Epub 2020 Nov 21. PubMed PMID: 33219599; PubMed Central PMCID: PMC8137717.

Clouston SAP, Deri Y, Horton M, Tang C, Diminich E, DeLorenzo C, Kritikos M, Pellecchia AC, Santiago-Michels S, Carr MA, Gandy S, Sano M, Bromet EJ, Lucchini RG, Luft BJ. Reduced cortical thickness in World Trade Center responders with cognitive impairment. Alzheimers Dement (Amst). 2020;12(1):e12059. doi: 10.1002/dad2.12059. eCollection 2020. PubMed PMID: 32695871; PubMed Central PMCID: PMC7364857.

Kritikos M, Clouston SAP, Diminich ED, Deri Y, Yang X, Carr M, Gandy S, Sano M, Bromet EJ, Luft BJ. Pathway Analysis for Plasma β-Amyloid, Tau and Neurofilament Light (ATN) in World Trade Center Responders at Midlife. Neurol Ther. 2020 Jun;9(1):159-171. doi: 10.1007/s40120-020-00189-1. Epub 2020 Apr 30. PubMed PMID: 32350803; PubMed Central PMCID: PMC7229074.

Kritikos M, Gandy SE, Meliker JR, Luft BJ, Clouston SAP. Acute versus Chronic Exposures to Inhaled Particulate Matter and Neurocognitive Dysfunction: Pathways to Alzheimer's Disease or a Related Dementia. J Alzheimers Dis. 2020;78(3):871-886. doi: 10.3233/JAD-200679. Review. PubMed PMID: 33074229; PubMed Central PMCID: PMC7704925.

Lodge D, Tidball P, Mercier MS, Lucas SJ, Hanna L, Ceolin L, Kritikos M, Fitzjohn SM, Sherwood JL, Bannister N, Volianskis A, Jane DE, Bortolotto ZA, Collingridge GL. Antagonists reversibly reverse chemical LTD induced by group I, group II and group III metabotropic glutamate receptors. Neuropharmacology. 2013 Nov;74:135-46. doi: 10.1016/j.neuropharm.2013.03.011. Epub 2013 Mar 26. PubMed PMID: 23542080.

Ling J, Kritikos M, Tiplady B. Cognitive effects of creatine ethyl ester supplementation. Behav Pharmacol. 2009 Dec;20(8):673-9. doi: 10.1097/FBP.0b013e3283323c2a. PubMed PMID: 19773644.